Paul P Tak Selected Research

Overweight

1/2015	Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals.
10/2013	Smoking and overweight determine the likelihood of developing rheumatoid arthritis.

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Paul P Tak Research Topics

Disease

161	Rheumatoid Arthritis 01/2023 - 01/2002
63	Inflammation (Inflammations) 01/2022 - 02/2002
55	Arthritis (Polyarthritis) 12/2022 - 10/2002
20	Psoriatic Arthritis 01/2022 - 10/2002
17	Experimental Arthritis 01/2016 - 01/2004
14	Synovitis 11/2020 - 08/2006
12	Necrosis 01/2018 - 01/2004
10	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 01/2009
10	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 01/2004
10	Rheumatic Diseases (Rheumatism) 11/2020 - 12/2008
10	Osteoarthritis 10/2020 - 01/2004
9	Neoplasms (Cancer) 11/2023 - 03/2007
7	Spondylarthritis (Spinal Arthritis) 10/2012 - 06/2006
6	Pain (Aches) 11/2020 - 01/2010
6	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019 - 03/2010
6	Infections 12/2016 - 04/2009
5	Joint Diseases (Joint Disease) 12/2017 - 06/2002
4	Osteitis 11/2020 - 04/2011
3	Glioblastoma (Glioblastoma Multiforme) 11/2023 - 01/2022
3	Arthralgia (Joint Pain) 12/2022 - 11/2020
3	Nasopharyngitis 11/2020 - 12/2017
3	Disease Progression 11/2014 - 09/2011
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 09/2012 - 01/2010
3	Atherosclerosis 03/2012 - 03/2007
3	Melanoma (Melanoma, Malignant) 01/2012 - 01/2009
2	Cough 11/2020 - 10/2020
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2019 - 10/2013
2	Injection Site Reaction 01/2018 - 01/2010
2	Erythema 12/2017 - 01/2017

Drug/Important Bio-Agent (IBA)

27	CytokinesIBA 01/2023 - 04/2002
26	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
24	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2004
20	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 03/2005
18	Rituximab (Mabthera)FDA Link 10/2019 - 03/2007
17	AutoantibodiesIBA 01/2022 - 07/2008
16	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 02/2002
14	Anti-Citrullinated Protein AntibodiesIBA 01/2023 - 11/2004
11	ChemokinesIBA 01/2018 - 01/2004
10	LigandsIBA 11/2020 - 07/2008
9	Rheumatoid FactorIBA 12/2022 - 11/2005
9	AntibodiesIBA 01/2021 - 11/2004
9	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2004
9	Infliximab (Remicade)FDA Link 08/2011 - 01/2004
8	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 06/2006
8	Antirheumatic Agents (DMARD)IBA 03/2016 - 06/2008
7	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2020 - 01/2004
6	Immunoglobulin M (IgM)IBA 12/2022 - 08/2011
6	Interleukin-17 (Interleukin 17)IBA 01/2022 - 01/2009
6	Adalimumab (Humira)FDA Link 01/2022 - 09/2010
6	Monoclonal AntibodiesIBA 01/2018 - 08/2006
6	EnzymesIBA 12/2017 - 01/2008
6	C-Reactive ProteinIBA 12/2017 - 01/2010
5	InterleukinsIBA 01/2022 - 02/2014
5	Interferon-betaIBA 01/2015 - 01/2002
5	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2015 - 01/2009
5	Interleukin-10 (Interleukin 10)IBA 01/2014 - 01/2006
4	RNA (Ribonucleic Acid)IBA 01/2023 - 07/2009
4	OtilimabIBA 11/2020 - 06/2015
4	Tumor Necrosis Factor InhibitorsIBA 01/2019 - 01/2009
4	Peptides (Polypeptides)IBA 01/2019 - 01/2006
4	Histone Deacetylases (Histone Deacetylase)IBA 01/2017 - 01/2008
4	Histone Deacetylase InhibitorsIBA 01/2017 - 03/2010
4	Phosphotransferases (Kinase)IBA 09/2015 - 05/2006
4	tocilizumab (atlizumab)FDA Link 01/2015 - 05/2011
4	Chemokine ReceptorsIBA 03/2013 - 05/2005
4	Etanercept (Enbrel)FDA Link 01/2013 - 03/2005
4	AntigensIBA 09/2012 - 01/2006
4	Therapeutic UsesIBA 03/2010 - 01/2002
4	NF-kappa B (NF-kB)IBA 06/2009 - 01/2004
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 04/2007
3	CC ChemokinesIBA 11/2020 - 11/2010
3	sirukumabIBA 01/2018 - 01/2017
3	Messenger RNA (mRNA)IBA 01/2018 - 11/2008
3	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2016 - 12/2008
3	Poly I-CIBA 01/2016 - 01/2012
3	CollagenIBA 01/2015 - 04/2010
3	ImmunosorbentsIBA 10/2014 - 11/2008
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 10/2014 - 08/2006
3	AngiopoietinsIBA 01/2014 - 08/2012
3	Abatacept (Orencia)FDA Link 08/2013 - 04/2011
3	Immunoglobulins (Immunoglobulin)IBA 06/2013 - 06/2011
3	Alefacept (Amevive)FDA Link 09/2012 - 10/2002
3	GTP Phosphohydrolases (GTPases)IBA 12/2010 - 01/2009
3	Collagen Type II (Type II Collagen)IBA 09/2010 - 01/2009
3	alpha7 Nicotinic Acetylcholine ReceptorIBA 09/2010 - 01/2009
3	HLA-DRB1 Chains (HLA DRB1)IBA 07/2009 - 06/2003
2	Ganciclovir (Cytovene)FDA LinkGeneric 01/2023 - 01/2022
2	Thymidine KinaseIBA 01/2023 - 01/2022
2	Interleukin-1 (Interleukin 1)IBA 01/2019 - 01/2010
2	Prostaglandins AIBA 01/2018 - 05/2011
2	Macrophage Colony-Stimulating FactorIBA 12/2016 - 03/2016
2	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 12/2016 - 03/2016
2	GSK1210151AIBA 02/2016 - 11/2014
2	Small Interfering RNA (siRNA)IBA 02/2016 - 03/2010
2	LipopolysaccharidesIBA 02/2016 - 03/2012
2	Interleukin-23 (Interleukin 23)IBA 01/2016 - 06/2012

Therapy/Procedure

42	Therapeutics 01/2023 - 02/2002
5	Aftercare (After-Treatment) 01/2023 - 03/2005
5	Biological Therapy 01/2017 - 06/2011
3	Immunotherapy 11/2023 - 06/2009